Accelerate your research
ERGO 2.0 provides a systems biology informatics toolkit centered on comparative genomics to capture, query, and visualize sequenced genomes. Using Igenbio's proprietary algorithms, and the most comprehensive genomic database integrated with the largest collection of microbial metabolic and non-metabolic pathways, ERGO™ assigns functions to genes, integrates genes into pathways, and identifies previously unknown or mischaracterized genes, cryptic pathways, and gene products.
ERGO 2.0’s hand-curated content combined with cutting edge genomics tools help scientists in the biotechnology, agriculture, and pharmaceutical industries understand and design the underlying biology leading to new products faster.
ERGO is the premier annotation platform, providing scientists and researchers with deep insight into their strains. Using a combination of proprietary algorithms, sequence similarity, gene context clustering, regulatory and expression data ERGO can deduce the core functionality of prokaryotic and eukaryotic genomes.
Visualize genomes by functional systems or subsystems and understand the distribution of metabolic and non-metabolic pathways. Powerful visualizations facilitate not only genome sequence comparison but also metabolic comparison for greater understanding of genome plasticity, gene displacement and orthologous displacements.
Integrate your expression data with ERGO to Identify differentially expressed genes from RNA-Seq, cDNA, EST, Microarray, and other expression studies. ERGO automatically performs statistical analysis presenting the differentially expressed genes in their metabolic context. No knowledge of statistical techniques or tools are necessary.
Explore the variation between your strains. ERGO identifies and annotates Single Nucleotide Polymorphisms (SNPs) and Insertions and Deletions (InDels). Quickly discover ablated transcripts, frameshifts, start/stop codon loss, and more.
ERGO 2.0 comes fully equipped with molecular biology tools such as primer design and restriction site analysis. Creating primers for protein expression, constructs, or gene knock outs is easy and fast.
ERGO 2.0 deduces the core metabolic functionality of a whole organism from genome sequence data.This enables scientists to accelerate their research for strain improvement, optimization, and product development.
ERGO 2.0 is a comprehensive genomics platform with a molecular cloning tool set. Seamless integration with Genome Compiler enables genes, operons, synthons, pathway systems, and cassettes to be edited with a modern synthetic biology environment. You can now easily create gene centric manipulations, restriction analysis, cloning, and expression systems from within ERGO.
ERGO 2.0 tools enable scientists to explore strain differences. Utilizing our publication proven Genome Align tool scientists are able to visually explore differences. Comparative protein clustering tools enhance identification of common and unique clusters or ORFs, highlighting features that could be used in generating primers for expression studies containing groups of organisms.
ERGO contains over 2700 manually curated genomes, over 8500 metabolic pathways, over 1 million unique, functional annotations, over 8.5 million protein sequences, over 20.5 million functional assignments and an astonoshing 8 billion orthologous protein connections. This unprecedented amount of quality curated data is the key that unlocks research. ERGO is updated every month with new and updated genomes.
ERGO's incredible proprietary database is now available via a Representational state transfer application programmer interface (REST API). Build your own proprietary applications on top of ERGO.
Easily import and export GFF, FASTA, GenBank, and other standard genomics formats.
ERGO 2.0 provides a platform for synthetic biology applications. Utilize engineering principles to design and create components such as devices, bricks, and synthons. ERGO's hand curated genomes and pathways provide a solid foundation for gene manipulation, vector construction, gene libraries, expression vectors, gene variants, diversity, fusions, strain development, protein modification, pathway engineering, protein expression, mutant constructs, and knockout strains. Its combinatorial platform is streamlined for molecular and synthetic biology for efficient product design and development.