Accelerate your research
ERGO 2.0 provides a systems biology informatics toolkit centered on comparative genomics to capture, query, and visualize sequenced genomes. Using Igenbio's proprietary algorithms, and the most comprehensive genomic database integrated with the largest collection of microbial metabolic and non-metabolic pathways, ERGO™ assigns functions to genes, integrates genes into pathways, and identifies previously unknown or mischaracterized genes, cryptic pathways, and gene products.
ERGO 2.0’s hand-curated content combined with cutting edge genomics tools help scientists in the biotechnology, agriculture, and pharmaceutical industries understand and design the underlying biology leading to new products faster.
Easily analyze your metagenome projects using ERGO by dragging and dropping your BIOM file into ERGO. Compute the Principal Coordinates Analysis (PCoA), Richness Estimates, and Taxonomic Bar Charts at a click of a button. In addition, ERGO computes Analysis of Similarities (ANOSIM) to test the significance of group differences.
Simple, Fast, and Secure sequence analysis.
ERGO Workflows could not be easier - simply drag and drop your sequence files into ERGO and start your analyzing. There is no simpler way to perform RNA-Seq and Variant analysis.
ERGO is the premier annotation platform, providing scientists and researchers with deep insight into their strains. Using a combination of proprietary algorithms, sequence similarity, gene context clustering, regulatory and expression data ERGO can deduce the core functionality of prokaryotic and eukaryotic genomes.
Visualize genomes by functional systems or subsystems and understand the distribution of metabolic and non-metabolic pathways. Powerful visualizations facilitate not only genome sequence comparison but also metabolic comparison for greater understanding of genome plasticity, gene displacement and orthologous displacements.
Integrate your expression data with ERGO to Identify differentially expressed genes from RNA-Seq, cDNA, EST, Microarray, and other expression studies. ERGO automatically performs statistical analysis presenting the differentially expressed genes in their metabolic context. Visualize your expression data on KEGG pathway maps. No knowledge of statistical techniques or tools are necessary.
Explore the variation between your strains. ERGO identifies and annotates Single Nucleotide Polymorphisms (SNPs), Insertions, and Deletions (InDels). Quickly discover ablated transcripts, frameshifts, start/stop codon loss, and more.
ERGO 2.0 deduces the core metabolic functionality of a whole organism from genome sequence data. This enables scientists to accelerate their research for strain improvement, optimization, and product development.
ERGO 2.0 tools enable scientists to explore strain differences. Utilizing our publication proven Genome Align tool scientists are able to visually explore differences. Comparative protein clustering tools enhance identification of common and unique clusters or ORFs, highlighting features that could be used in generating primers for expression studies containing groups of organisms.
Access ERGO through our secure cloud from anywhere in the world. Your data is encrypted at all times; at rest and in transit. Private cloud and secure internal network installations are also available. Contact us for details.
ERGO contains over 300 manually curated genomes, over 8500 metabolic pathways, over 1 million unique, functional annotations, over 10 million protein sequences, over 20.5 million functional assignments and an astonoshing 11 billion orthologous protein connections. This unprecedented amount of quality curated data is the key that unlocks research. ERGO is updated every month with new and updated genomes.
ERGO's incredible proprietary database is now available via a REST API. This enables you to upload and download data from your own proprietary applications.
Easily import and export GFF, FASTA, GenBank, and other standard genomics formats.